| Date | Location | Result | |
| Nov 20, 2010 | Conway, AR | Central Arkansas 28, McNeese State 24 | |
| Nov 13, 2010 | Lake Charles, La | McNeese State 36, TXST 6 | Box score |
| Nov 06, 2010 | Huntsville, Tex. | McNeese State 33, Sam Houston 28 | |
| Oct 30, 2010 | Lake Charles, La | McNeese State 24, NICH 14 | Box score |
| Oct 23, 2010 | Hammond, La. | McNeese State 13, Southeastern La. 10 | |
| Oct 16, 2010 | Baton Rouge, La. | LSU 32, McNeese State 10 | |
| Oct 09, 2010 | Lake Charles,La | SFA 32, McNeese State 27 | Box score |
| Oct 02, 2010 | Natchitoches, La. | McNeese State 24, Northwestern State 7 | |
| Sep 25, 2010 | Lake Charles, La. | Cal Poly 40, McNeese State 14 | Box score |
| Sep 11, 2010 | Columbia, Mo. | Missouri 50, McNeese State 6 | |
| Sep 04, 2010 | Lake Charles, LA. | McNeese State 30, Lamar 27 | Box score |